on Erectile Dysfunction & Impotence
A. Adimoelja and P. Ganeshan Adaikan
Airlangga University, Indonesia and National University of Singapore
in 6th Biennial Asian-Pacific
in Meeting on Impotence in Kuala Lumpur, Malaysia (1997)
Int. J. Impotence Research v9, supp 1 (1997)
An interesting correlation of dehydroepiandrosterone-sulphate (DHEA-S)
level with the incident of low sex drive and higher occurrence of
impotence was discovered in studies with patients diagnosed with
diabetes mellitus. To test further the relationship between DHEA-S
and erectile dysfunction (ED), we conducted a clinical trial of
30 non-diabetic men with ED, 30 non-diabetic men without ED and
15 diabetic men with ED. These men are given extract of Tribulus
terrestris (Libilov) at 3 x 250 mg / day for 3 weeks. The DHEA-S
levels, as well as other blood and liver parameters were evaluated.
We found a significant increase of DHEA-S levels in diabetic and
non-diabetic subjects after treatment, and a significant increase
in the frequency of successful intercourse by 60% in both the diabetic
and non-diabetic groups with or without ED.
Academic Hospital Dr. Soetomo, Airlangga University, Surabaya, Indonesia
in Seminar of Erectile Dysfunction of Diabetes in Bandung, Indonesia
Diabetes mellitus is a systemic metabolic disease which results
in the destruction or weakening of many tissues and cell types.
Here we conduct a preliminary clinical study to determine the level
of dehydroepiandrosterone-sulphate (DHEA-S) in 15 diabetic males
and 15 healthy controls. This study shows that the DHEA-S levels
in healthy people are significantly higher than that found in diabetic
subjects. A further study conducted with 30 male subjects with diabetes
shows that those also suffering from erectile dysfunction (ED) have
even lower DHEA-S levels than those without the dysfunction.
Treatment of diabetic subjects with protodioscin in form of tablets
of Tribulus terrestris L extract (Libilov, 250 mg at 3 x 1 tablet
daily for ten days) results in the increase of DHEA-S levels of
these subjects, with the most gain experienced by those who also
suffer from ED.
Moreover, in this study we notice a significant increase (>
60%) in the frequency of successful sexual intercourse, as well
as increased libido or sex drive in the diabetic male subjects.
In this clinical study, we find no unwanted side-effects of administration
of Libilov as examined by laboratory blood tests, as well as kidney
and liver function tests.
Medical Biology Division of Andrology, University of Sriwijaya,
We conducted this trial to study the effect of Tribulus terrestris
(protodioscin) supplement on the sense of well-being and sexual
response of men suffering from diabetes mellitus. 30 men between
the ages of 40 to 55 years were divided into two 15-men groups.
The experimental and control groups were given Tribulus terrestris
extract (Libilov tablets, 250mg) and placebo pills 3 times per day
for 30 days, respectively. Both groups were not statistically different
in age, body weight and fasting sugar levels.
Our result showed that the Tribulus supplement is able to improve
the sense of well being and sexual response of diabetic subjects.
We found improvement in sex drive, erection, ejaculation and orgasm
in the treated group and no improvement in these parameters in the